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2016年12月1日星期四

What is glomerulonephritis?

What is glomerulonephritis? The rigorous formulation is called glomerular disease, those diseases by glomerular functions and morphology injury in structure. Glomerular have many etiologies and mechanism, pathology types different, but have same clinical symptoms. Filtration function obstacle in glomerular maybe cause protein and red blood cell into urine, need to remove excess water and toxin retention retention lead hypertension, swelling, acid-base imbalances and electrolyte disorder. If diagnosis had other disease affect kidney cause glomerular disease such systemic lupus erythematosus cause kidney injury called secondary glomerulonephritis. If doctors did not found other disease could affect kidney, it is called primary glomerulonephritis.
What sign or symptom for glomerulonephritis? Urine abnormal: Of urine contains a lot of bubbles, and continue, urine look like brown or hemourine, excessive urination at night. Swelling: face or ankle swelling. Hypertension: younger patients not specially family history or blood pressure rapid change, and need too many anti-hypertension drug, should vigilant kidney disease. Unknown origin anemia, and have pale ,weak and chest tightness by anemia.
Base primary glomerulonephritis common clinical symptom could included five types: acute diffuse proliferactive glomerulonephritis, rapid progressive glomerulonephritis, chronic glomerulonephritis, nephrotic syndrome.
What is acute diffuse proliferactive glomerulonephritis? It also called acute nephritis, Course within 3 months more, illness weight is different. Common symptoms included hemourine (gross hematuria or microscopic hematuria), proteinuria and cylindruria, also have hypertension and swelling, could have short time kidney function injury.
What is rapidly progress glomerulonephritis? Acute, seriously and make rapidly progress, common have swelling, hemouria, proteinuria and cylindruria, also always have hypertension and rapidly progress anemia, could performance nephrotic syndrome. When kidney function injury progress seriously could lead oliguria or anuria. If illness failed to control, several weeks to months can cause kidney failure, require renal replacement therapy to lengthen life.
What is latent glomerulonephritis? Asymptomatic hemouria and/or proteinuria, not had acute or chronic nephritis or other kidney disease history, kidney function normal, also not clinical sign and symptoms, always have simple proteinuria or/and source of glomerular hematuria. Those patients most common found abnormal in conventional check-up.
How to treatment glomerulonephritis? 1) Keep kidney function normal, or delay kidney function decreased; 2) prevention or treat Glomerulonephritis associated complications such as nephrotic syndrome maybe lead infections, thrombus and hyperlipemia; 3) improve life quality, reduce anxiety.

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