Primary causes of Nephrotic Syndrome
Nephrotic Syndrome is usually caused by damage to the filters (glomeruli) in
your kidneys. In normal case, the glomeruli in your kidneys are filtering blood
as it flows through your kidneys and they can separate the useful things from
wastes. Healthy glomeruli can keep proteins in blood to maintain the right
amount of fluid in your body. However, once your glomeruli are damaged, they
will allow too much blood proteins leak into urine thus resulting in Nephrotic
Syndrome. The common causes of Nephrotic Syndrome could be listed as the
following:
Minimal kidney disease: It is the most common cause of Nephrotic Syndrome in
children. This disorder can result in abnormal renal function. However, the
result of microscope test usually does not show abnormality.
Focal segemental glomerulosclerosis: A part of glomeruli in kidneys are
scarred or sclerotic. It may result from another disease or a genetic defect or
occur for no reason.
Membranous nephropathy: It refers to the thickening of glomerular membrane.
Secondary causes of Nephrotic Syndrome
Diabetes Mellitus: Long-term high blood glucose can damage the filters in
kidneys thus resulting in Nephrotic Syndrome.
Systemic lupus erythematosus( SLE): It is a autoimmune disorder than can
involve multiple organs including kidneys. It can cause inflammation of
glomeruli.
Amyloidosis: It is attributed to the proteins building up in blood and it can
affect multiple organs including kidneys. It can damage the filters in kidneys
thus resulting in Nephrotic Syndrome.
Viral infection: The common viral infections mainly include hepatitis B,
hepatitis C etc.
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