unless progressive damage to the kidneys severely interferes with their normal function. In this case, people with the disease may experience symptoms as below.
• Foamy or frothy urine
This is due to excessive Protein in Urine. The glomeruli of the kidneys have responsibility of regulating protein levels in the urine. When the glomeruli become damaged or scarred, they are unable to prevent protein from leaving the body in the urine, proteinuria presents. When protein from the urine hits the toilet bowl after urination, foamy or frothy urine is produced.
• Swelling, or edema
Some patients with FSGS develop swelling (edema) of the eyelids in the morning and swollen of the legs, ankles, feet, hands, face or abdomen late in the day due to fluid retention.
• High Blood Pressure
Elevated blood pressure is often seen with primary FSGS. Many patients will have hypertension at the time of diagnosis.
• Poor Appetite
Loss of appetite may be result from buildup of toxins in the body due to kidney dysfunction of filtering toxic wastes, medicines, and diet changes.
• Fatigue
Fatigue in kidney disease is most often caused by anemia, a shortage of oxygen-carrying red blood cells.
• Weight gain
If the body retains water, rapid weight gain may be caused.
• Nausea and/or vomiting
With severely damaged kidney function, large amount of nitrogen will buildup in the blood and stimulate the gastrointestinal tract, resulting in nausea and/or vomiting.
Other signs and symptoms of FSGS may also include pain of back (flank and abdomen), low blood protein, high blood cholesterol level, fever and chill, etc. If you have some of the above discomforts, see your doctor to discuss what might be causing them and corresponding treatment.
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