High creatinine
High creatinine refers to creatinine value is higher than normal,
creatinine including serum creatinine and urine creatinine, but serum creatinine
is more meaningful to measure renal function. So high creatinine is generally
refers to serum creatinine is on the high side. Serum creatinine in each
hospital is not the same as the measure of normal, serum creatinine in general
normal standard is: 44-133 mu mol/L, when more than 133 mu serum creatinine
mol/L means that the kidney damage, have renal insufficiency, renal failure.
More than 133 mol/L for inflammatory lesions, 186 mu of mol/L for renal damage,
451 mu of mol/Lfor renal failure.
Symptoms of high creatinine
Symptoms of high creatinine value, mainly include the following: 1. The
edema often begin with eyelid edema (a part of patients from the first leg),
seriously affected the body appear even pleural effusion and ascites. 2. High
blood pressure is one of the high creatinine value performance. 3. The frequency
(more), urgency, (can not to suppress the urine), urine pain (the lower abdomen
pain and urethra to pass urine). 4. The waist pain mostly dull pain, surgical
disorders can appear severe cramping. 5. Blood in the urine blood is contained
in the urine, or assay in positive occult blood (a plus). 6.more Urine: every
day more than 2500 ml. 7. Oliguria or anuria every day less than 400 ml of
oliguria, less than 100 ml anuria. 8. Urine bubble may be a manifestation of
urine protein increased more, assay of urine protein positive is reliable
evidence of urine protein increased.
Significance of high creatinine
When serum creatinine is significantly higher than normal, often has
serious damage to kidney function. After the serum creatinine increased, the
most important thing is to take measures to treat, although may be increased
serum creatinine is not much, but has become a serious kidney damage, because
the kidneys have strong compensatory function, the mild and moderate damage,
increased serum creatinine may not be obvious, normal renal injury by more than
80%, increased serum creatinine is obvious. Therefore, once found an increased
serum creatinine should cure of as soon as possible.
Examine of high creatinine
When patients with elevated creatinine should first pay attention to not
disorderly use the drug induced renal damage, such as: pain killers. Secondly,
come to the hospital regularly, then observe the changes of creatinine and urea
nitrogen. Again, don't tired, don't stay up late, proper exercise, ready to
prevent an infection. Finally is scientific and reasonable diet, give priority
to with light diet, don't eat rich food, contains high purine food also cannot
eat, can eat foods contain high quality protein but the amount not much, edema
and hypertension eat salt restriction.
When creatinine increased patients will have symptoms, it's just ignored by
people. When people's increased creatinine value will appear after night urine,
fatigue, thirst, body appears edema, blood pressure, heart failure, the symptom
such as pulmonary edema, which is the performance of water metabolism imbalance.
Occurs when there is a metabolic acidosis patients don't want to eat, weakness,
restlessness, abdominal pain, vomiting, and even coma. These are obvious
symptoms, in addition to patients with elevated creatinine by checking also
found to have high and low sodium, high and low potassium hematic disease, slow
growth, such as sexual dysfunction, which is also an expression of the high
creatinine. When people of the above symptoms should make a detailed physical
examination to the hospital, don't ignore believed to be caused by fatigue.
Harm of high creatinine
harm is mainly manifested in the following several aspects:
first, the sodium metabolism imbalance: high creatinine will
appearhyponatremia or high sodium.
Two, potassium metabolism disorders: high creatinine often accompanies a
hyperkalemia or hypokalemia.
Three, water metabolism disorders: including polyuria, nocturia increased,
thirst, dry mucosa, fatigue, etc.; Or systemic edema, high blood pressure,
pulmonary edema and heart failure, etc.
Four, aluminum, magnesium, copper, zinc, selenium metabolic abnormalities,
etc.
Five, renal bone disease: bone pain and proximal muscle weakness; Bone pain
is often generalized, pragmatic under bust bone and skeletal deformities can
cause symptoms such as short stature.
Six, metabolic acidosis: patients with high creatinine can have large and
long deep breathing, lack of appetite, abdominal pain and nausea, vomiting,
weakness, headache, restlessness, and even coma.
Seven, blood system disease, such as renal anemia, etc. High on behalf of
glomerular filtration rate and serum creatinine kidney detoxification function
decline, at this point, the kidney disease in patients with renal function
damage, entered the stage of renal insufficiency. And with the increase of serum
creatinine index continued, the patient's kidney function damage degree will be
more and more serious, normal creatinine between 40 ~ 120. If creatinine above
this range, then process into the kidney in patients with pathological changes,
creatinine tall if not treated, can cause great harm, but also develop into
uremia.
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