SHIJIAZHUANG KIDNEY DISEASE HOSPITAL
What causes nephrotic syndrome?
The kidneys have tiny blood vessels called glomeruli that filter waste and extra water from the blood. Healthy kidneys keep the right amount of protein in the blood. Protein helps move water from the tissues into the blood. When the tiny filters are damaged, too much protein slips from the blood into the urine. As a result, fluid builds up in the tissues and causes swelling.
Nephrotic syndrome is often caused by:
A type of kidney disease called minimal change disease (or nil disease). This is the main cause of nephrotic syndrome in children. Doctors don't know what causes minimal change disease.
Diabetes. This is the most common cause of nephrotic syndrome in adults.
Many other things can cause the blood vessel damage that leads to nephrotic syndrome, including:
Kidney diseases that attack the glomeruli, such as membranous glomerulopathy and focal segmental glomerulosclerosis.
Diseases such as lupus and certain cancers.
Infections, such as HIV, hepatitis B, and hepatitis C.
Medicines such as nonsteroidal anti-inflammatory drugs.
Sometimes doctors don't know what causes it.
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